Ammonium Carbamate is a white crystal with the following properties:

Molecular formula: CH6N2O2
Solubility: easily soluble in water, insoluble in ether organic solvents
Stability: Stable in dry air, but in humid air will emit ammonia gas and change into ammonium bicarbonate
Temperature effect: Decomposition begins at 35℃ and is completely decomposed into ammonia and carbon dioxide at 59℃.

 

Ammonium Carbamate has a wide range of uses, including but not limited to:

Pharmaceutical industry: Used as an intermediate for aluminum phosphide and the production of medicine and pharmaceutical reagents.
Pesticide field: As an intermediate of pesticides.
Fertilizer manufacturing: As a source of nitrogen, it can be used in the production of urea.
Electronic component manufacturing: As an etching agent, cleaning agent and other purposes.
Organic synthesis: As a catalyst, involved in a variety of reactions.

 

1. Ammonium Carbamate has a variety of applications in the pharmaceutical industry, mainly including:

• Pharmaceutical intermediates: Used as an intermediate for aluminum phosphide, and is also used in the production of pharmaceutical, pharmaceutical reagents and other fields.

•Fermentation accelerator: It is also used as a fermentation accelerator to aid in the fermentation process of pharmaceutical products.

 

2. The application in the field of pesticides, mainly as an intermediate of pesticides. The following are its specific uses:

• Synthetic herbicides:
Ammonium Carbamate is one of the important intermediates in the production of glyphosate. Glyphosate is a broad-spectrum herbicide widely used in agriculture to control weed growth.

• Synthetic fungicides:
In the synthesis of some fungicides, it may also be used as a raw material for the reaction or as part of an intermediate step.

• Regulating soil pH:
Although this is not used directly as a pesticide, Ammonium Carbamate is able to regulate the pH value of the soil, indirectly affecting the effect of pesticides and plant absorption.

• Promote crop growth:
Under the right conditions, ammonia and carbon dioxide produced by the decomposition of Ammonium Carbamate can provide nutrients for plants and promote crop growth.

 

3. The application in fertilizer manufacturing is mainly reflected in its use as one of the raw materials for urea production.

Urea is a fertilizer with high nitrogen content and is widely used in agriculture as a fertilizer and feed additive. In addition, urea plays an important role in the chemical and pharmaceutical industries.

In the production process of urea, it can be prepared by a thermal conversion method. This process is carried out at temperatures of 200℃ and pressures of 130-200 bar, where ammonia (NH3) and carbon dioxide (CO2) react to form urea. The reaction mixture is expanded to atmospheric pressure and then separated by distillation column at 70℃. Due to incomplete reaction, residual Ammonium Carbamate is striped and decomposed in the environment of NH3 and CO2, thus recovering feedstock and improving production efficiency.

In general, the application of Ammonium Carbamate in fertilizer manufacturing is mainly through the process of its conversion to urea, which not only provides high-quality urea products, but also improves production efficiency and resource utilization.

 

4. The use in the manufacture of electronic components is mainly concentrated in the following aspects:

• Etching agent:
In some specific etching steps, Ammonium Carbamate solutions can be used to selectively remove specific materials, such as silicon or silica.
Compared to other strong acid or alkali etchers, Ammonium Carbamate is chemically mild, enabling precise control without damaging the underlying material.

• Cleaning agent:
Used as a cleaning step in semiconductor manufacturing to remove organic residues, metal ions and other impurities.
Compared with traditional organic solvents, Ammonium Carbamate has lower toxicity and environmental impact.

• Dopants:
In certain cases, Ammonium Carbamate can act as a doping source, introducing specific impurity elements into the semiconductor lattice to adjust its electrical properties.
It is mainly used for doping processes of silicon and other III-V compound semiconductors.

• Buffer composition:
Due to its good buffering capacity, Ammonium Carbamate can be used to prepare stable solution environments in various chemical or electrochemical processes.
In the manufacture of precision electronic components, a stable pH value is essential to ensure consistent product quality.

 

5. Ammonium Carbamate has many important uses in organic synthesis, mainly including:

• Catalytic transfer hydrogenation reaction:
Ammonium Carbamate, as a common reducing agent, shows good selectivity and reduction efficiency in catalytic transfer hydrogenation.
This reaction is particularly suitable for the reduction of nitro, cyano, azide, azo and other functional groups, but can also be used to remove protective groups such as CBZ and O-BN groups.

• cyclization reaction:
In organic synthesis, used in cyclization reactions, such as the synthesis of intermediates for drugs.

• Formylation reaction:
Used as a formylation reagent for the synthesis of N-formylated secondary amines and anilines.

• Carbonyl reduction to amine:
When used with a hydrogen-reducing agent, can efficiently reduce aldehydes or ketones to the corresponding amines.