2-Aminophenol, also known as O-Aminophenol or o-Hydroxyaniline. is an aromatic organic compound with the molecular formula C₆H₇NO and CAS Number 95-55-6. It appears as white to off-white or beige crystalline powder or needles that may darken upon exposure to air or light. It is slightly soluble in water while being readily soluble in ethanol.
This versatile organic compound serves as a key building block in the production of hair dyes, photographic chemicals, pharmaceutical intermediates, and heterocyclic compounds.
Technical Specifications
| ITEMS | SPECIFICATIONS |
| Appearance | White acicular crystal |
| Purity | ≥99.0% |
| Moisture | ≤0.5% |
| Ash Content | ≤0.2% |
| Melting Point | 170.0-176.0℃ |
Package & Storage
- Packed in plastic woven bags, net weight 25kg/bag.
- Keep in a cool, dry, well-ventilated place away from light, air, heat, and strong oxidizing agents.
Key Benefits and Properties of 2-Aminophenol
Versatile Intermediate:
Excellent building block for heterocyclic compounds used in pharmaceuticals, agrochemicals, and functional materials.
Dye Precursor:
Widely used in oxidative hair dye formulations to produce a range of shades, especially browns and blacks.
Reducing Agent:
Acts as a reducing agent in chemical reactions and historical photographic developers.
Amphoteric Nature:
Exhibits both acidic (phenolic) and basic (amino) properties, enabling diverse reactivity.
High Reactivity:
Readily undergoes oxidation, condensation, and cyclization reactions for custom synthesis.
Applications and Uses of 2-Aminophenol
2-Aminophenol finds extensive use across multiple industries due to its multifunctional chemistry:
Hair Dye and Cosmetics Industry:
Primary precursor in permanent oxidative hair coloring products. It reacts with couplers and oxidants (such as hydrogen peroxide) to form vibrant, long-lasting colors.
Pharmaceuticals and Organic Synthesis:
Key starting material for the synthesis of benzoxazole, benzimidazole, quinoline, and other heterocyclic compounds used in drugs, agrochemicals, and specialty materials.
Photography:
Historically employed as a developing agent in black-and-white photographic processing due to its reducing properties.
Dyes and Pigments:
Intermediate for the production of various azo dyes, sulfur dyes, and other colorants.
Other Industrial Uses:
Chemical research, corrosion inhibitors, and as a building block in advanced materials.
Frequently Asked Questions (FAQs)
Q: What are the main applications of 2-Aminophenol?
A: It is primarily used as an intermediate in hair dyes, pharmaceutical synthesis (especially heterocycles like benzoxazoles), dyes/pigments, and historically in photography.
Q: Is 2-Aminophenol safe to handle?
A: It is harmful if swallowed or inhaled and suspected of causing genetic defects. Proper PPE, ventilation, and adherence to SDS guidelines are essential.
Q: How should 2-Aminophenol be stored?
A: Store in a cool, dry, dark place in tightly sealed containers, protected from air, light, heat, and oxidizing agents to prevent discoloration and degradation.
Q: Does 2-Aminophenol darken over time?
A: Yes, like many aminophenols, it can darken when exposed to air or light. Proper storage minimizes this effect.
Q: Is 2-Aminophenol used in permanent hair dyes?
A: Yes, it is a common precursor in oxidative hair coloring formulations, contributing to color development when oxidized.
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