Glutaraldehyde, also known as pentanedial or glutaral, is an organic dialdehyde with the chemical formula C₅H₈O₂ and CAS Number 111-30-8. It appears as a colorless to pale yellow oily liquid with a sharp, pungent odor. It is widely used as a high-level disinfectant, sterilant, and industrial biocide.
Technical Specifications
| ITEMS | SPECIFICATIONS |
| Appearance | Colorless to light yellow transparent liquid |
| Glutaraldehyde Content | ≥50% |
| PH Value | 3.1-4.5 |
| Color (Pt/Co) | ≤50 |
| Methanol | ≤0.5% |
| Density (g/ml@20℃) | 1.127-1.133 |
Package & Storage
- 25kg or 220kg/plastic drum or 1100kg/IBC tank.
- Stored in a cool, well-ventilated area; tightly closed containers to minimize polymerization and vapor release.
Benefits of Glutaraldehyde
Broad-Spectrum Biocidal Activity:
Effective against bacteria (Gram-positive and Gram-negative), viruses, fungi, mycobacteria, and bacterial spores.
High-Level Disinfection and Sterilization:
Ideal for heat-sensitive medical instruments where heat or steam cannot be used.
Cross-Linking Agent:
Provides strong protein fixation for histology, electron microscopy, and tissue preservation.
Industrial Biocide:
Controls microbial growth in cooling towers, oil & gas pipelines, and process water systems to prevent corrosion and biofouling.
Rapid Action:
Achieves disinfection in minutes to hours depending on concentration and activation.
Compatibility:
Works well in various formulations and systems with proper handling.
Applications and Uses of Glutaraldehyde
Glutaraldehyde serves critical roles across multiple industries:
Healthcare and Medical
- High-level disinfectant and cold sterilant for heat-sensitive instruments (endoscopes, bronchoscopes, dialysis equipment, surgical tools).
- Used in activated solutions (e.g., 2% concentration) for immersion disinfection.
Laboratory and Histology
- Tissue fixative in electron microscopy, light microscopy, and histochemistry.
- Cross-linking reagent for proteins and biological samples.
Industrial and Water Treatment
- Biocide in cooling towers, recirculating water systems, air washers, and pasteurizers to control algae, bacteria, and biofilms.
- Microbial control in oil & gas operations (pipelines, fracking fluids, storage tanks) to prevent sulfate-reducing bacteria and corrosion.
Other Industrial Uses
- Leather tanning agent for softening and mold resistance.
- Preservative in metalworking fluids, paper production, and textile processing.
- Hardener in X-ray film developers.
- Sanitizer in animal housing, poultry facilities, and aquaculture.
Frequently Asked Questions (FAQs)
Q: What are the primary applications of Glutaraldehyde?
A: Glutaraldehyde is primarily used as a high-level disinfectant/sterilant for medical instruments, a tissue fixative in labs, a biocide in industrial water treatment and oil & gas, and a tanning agent in leather processing.
Q: How should Glutaraldehyde solutions be activated for disinfection?
A: Commercial glutaraldehyde is supplied acidic for stability. For high-level disinfection, activate with an alkaline buffer (e.g., sodium bicarbonate) to raise pH to ~7.8–8.0, optimizing biocidal efficacy.
Q: What safety precautions are needed when handling Glutaraldehyde?
A: Use PPE (gloves, goggles, respirators), ensure good ventilation or enclosed systems, avoid skin/eye contact and inhalation.
Q: Does Glutaraldehyde have environmental concerns?
A: Yes, it is toxic to aquatic life. Prevent release into waterways and dispose according to local hazardous waste regulations.
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