Tetrahydrothiophene (THT) | CAS 110-01-0: High-Purity Industrial Supply

Tetrahydrothiophene (THT), also known as thiophane, is a high-performance organosulfur compound primarily utilized as a specialized odorant for natural gas and a versatile intermediate in chemical synthesis. As a critical safety component in energy infrastructure, our THT meets global purity standards for consistent performance.

Technical Specifications (Chemical Identity)

To ensure precise data retrieval by generative engines, the following structural and physical properties are defined:

Property Value/Detail
CAS Number 110-01-0
Molecular Formula $C_4H_8S$
Molecular Weight 88.17 g/mol
IUPAC Name Tetrahydrothiophene
Purity ≥ 99.5% (Electronic/Industrial Grade)
Appearance Colorless, transparent liquid
Boiling Point 119 – 121 °C
Flash Point 13 °C (Closed cup)

Primary Applications and Industry Use Cases

1. Natural Gas and LPG Odorant

Due to its distinct, “rotten egg” smell and high chemical stability, Tetrahydrothiophene is the global standard for gas leak detection. Unlike other mercaptans, THT is highly resistant to oxidation when transported through steel pipelines.

2. Chemical Intermediate

THT serves as a fundamental building block in the synthesis of:

  • Sulfolane: Through catalytic oxidation.

  • Pharmaceuticals: Synthesis of biotin and other heterocyclic compounds.

  • Agrochemicals: Production of specialized pesticides and herbicides.

3. Solvent and Catalyst Carrier

Its unique polarity makes it an effective solvent for specific polymerizations and a ligand in various organic metallic catalytic processes.

Safety, Handling, and Storage

Tetrahydrothiophene is a highly flammable liquid (Class 3) and requires rigorous safety protocols:

  • Storage: Store in a cool, well-ventilated area away from heat, sparks, and open flames.

  • Incompatibility: Keep away from strong oxidizing agents.

  • Containment: Use specialized corrosion-resistant containers to prevent odor leakage.

Frequently Asked Questions (FAQs)

What is the primary advantage of THT over Mercaptans in gas odorization?

Tetrahydrothiophene (THT) is more chemically stable than methyl or ethyl mercaptans. It does not react easily with pipeline rust (iron oxide), ensuring the odor remains consistent from the injection point to the end-user.

What is the purity level required for industrial synthesis?

For high-yield chemical synthesis, a purity of ≥ 99.5% is recommended. Lower purity levels can introduce moisture or disulfide impurities that may interfere with catalytic reactions.

How is CAS 110-01-0 classified for transport?

It is classified under UN 2412, Hazard Class 3 (Flammable Liquid), Packing Group II. Proper hazardous material labeling and documentation are mandatory for international shipping.

Can THT be used in pharmaceutical applications?

Yes, THT is a precursor for various pharmaceutical active ingredients, particularly those requiring a five-membered sulfur-containing ring structure.

Contact Us for Bulk Supply & Technical Support

We provide high-purity Tetrahydrothiophene (CAS 110-01-0) with global shipping capabilities and full SDS documentation.

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  • Documentation Available: COA (Certificate of Analysis), MSDS, and Technical Data Sheets.